Clinical Criteria
ADD/ADHD Agents (Revised September 27, 2021)*
Aliskiren Containing Agents (Pending Implementation) (Revised February 17, 2021)
Aliskiren Containing Agents (Revised March 21, 2019)*
Allergen Extracts (Revised December 10, 2019)*
Altabax (Revised February 17, 2021)*
Amantadine ER (Pending Implementation) (Revised January 27, 2021)*
Androgenic Agents (Pending Implementation) (Revised March 21, 2019)*
Antiemetic Agents (Revised February 17, 2021)*
Antipsychotic Agents (Revised February 17, 2021)*
Anxiolytics and Sedative-Hypnotics (Pending Implementation) (Revised July 23, 2021)*
Anxiolytics and Sedative-Hypnotics (Revised March 22, 2019)*
Arikayce (Pending Implementation) (Revised February 17, 2021)*
Binge Eating Disorder (BED) Agents (Pending Implementation) (Revised March 1, 2021)*
Buprenorphine Agents (Revised July 19, 2021)*
Carisoprodol Overuse (Revised March 26, 2019)*
Carisoprodol-Containing Agents (Pending Implementation) (Revised May 23, 2019)*
CGRP Antagonists, Acute (Pending Implementation) (Revised October 8, 2021)*
CGRP Antagonists, Chronic (Pending Implementation) (Revised October 7, 2021)*
CNS Stimulants (Revised October 29, 2019)*
Colcrys (Pending Implementation) (Revised February 17, 2021)*
Cough & Cold Agents (Revised March 10, 2020)*
COX-2 Inhibitors (Revised February 18, 2021)*
Cyclobenzaprine (Revised March 27, 2019)*
Cymbalta (Pending Implementation) (Revised January 30, 2020)*
Cystic Fibrosis Agents (Pending Implementation) (Revised July 1, 2021)*
Cystic Fibrosis Agents (Revised January 20, 2021)
Cytokine and CAM Antagonists (Pending Implementation) (Revised September 23, 2021)*
Cytokine and CAM Antagonists (Revised March 2, 2021)*
Desmopressin (Revised December 21, 2020)*
Dextromethorphan Overutilization (Revised December 30, 2019)*
Diabetic Test Strips (Pending Implementation) (Revised March 27, 2019)*
Diacomit (Pending Implementation) (Revised August 20, 2020)*
Diclofenac (Pending Implementation) (Revised March 27, 2019)*
Dopamine Agonists (Pending Implementation) (Revised January 22, 2021)*
Doxylamine/Pyridoxine (Pending Implementation) (Revised October 29, 2019)*
DPP4 Inhibitors (Revised March 27, 2019)*
Drug Regimen Optimization (Pending Implementation) (Revised November 11, 2019)*
Drug Regimen Optimization (Revised September 16, 2019)*
Dupixent (Revised March 3, 2021)*
Duplicate Therapy (Revised August 17, 2021)*
Emflaza (Pending Implementation) (Revised October 7, 2021)*
Emflaza (Revised July 3, 2019)*
Enzymes (Pending Implementation) (Revised April 5, 2021)*
Enzymes (Revised September 11, 2019)*
Epidiolex (Pending Implementation May 11, 2021) (Revised February 25, 2021)*
Erythropoiesis-Stimulating Agents (Revised October 7, 2020)*
Evrysdi (Pending Implementation) (Revised January 22, 2021)*
Fentanyl Agents (Revised July 19, 2021)*
Forteo (Pending Implementation) (Revised March 28, 2019)*
Gabapentin Agents (Revised March 29, 2019)*
Gaucher's Disease Agents (Pending Implementation) (Revised July 15, 2019)*
GI Motility Agents (Pending Implementation) (Revised July 30, 2019)*
GI Motility Agents (Revised March 29, 2019)*
Glatiramer Acetate Injection (Pending Implementation) (Revised July 15, 2019)*
GLP-1 Receptor Agonists (Revised June 1, 2021)*
Growth Hormone Agents (Revised June 8, 2021)*
Growth Hormone Quick Reference Guide
HAE Agents (Pending Implementation) (Revised July 1, 2021)*
Hemady (Pending Implementation) (Revised March 29, 2021)*
HP Acthar (Pending Implementation) (Revised July 24, 2020)*
HP Acthar (Revised July 15, 2019)*
Hyperlipidemia Agents (Formerly PCSK9 Inhibitors) (Revised March 29, 2019)*
Hyperlipidemia Agents (Pending Implementation December 7, 2021) (Revised October 7, 2021)*
Imiquimod (Revised March 29, 2019)*
Increlex (Revised March 29, 2019)*
Inhaled Antibiotics (Pending Implementation) (Revised February 13, 2020)*
Ketorolac (Revised March 29, 2019)*
Keveyis (Pending Implementation) (Revised March 29, 2019)*
Leukotriene Modifiers (Revised July 15, 2019)*
Lidocaine Patches (Pending Implementation) (Revised July 15, 2019)*
Lovaza (Revised June 18, 2021)*
Lyrica (Pending Implementation) (Revised June 26, 2020)*
Makena (Revised May 14, 2019)*
Monoclonal Antibody Agents (Fasenra and Nucala) (Pending Implementation December 14, 2021) (Revised August 9, 2021)*
Monoclonal Antibody Agents (Fasenra and Nucala) (Revised February 1, 2021)*
Multiple Sclerosis Agents (Pending Implementation) (Revised July 23, 2021)*
Nitazoxanide (Formerly Alinia) (Revised February 17, 2021)*
NItazoxanide (Pending Implementation November 23, 2021) (Revised September 7, 2021)*
Nuedexta (Revised March 29, 2019)*
Nuplazid (Pending Implementation) (Revised March 29, 2019)*
Ophthalmic Immunomodulators (Pending Implementation) (Revised October 7, 2021)*
Opiate Overutilization (Revised July 27, 2020)*
Opiate/Benzodiazepine/Muscle Relaxant Combinations (Revised January 30, 2020)*
Oriahnn (Pending Implementation) (Revised October 28, 2020)*
Orilissa (Pending Implementation) (Revised March 29, 2019)*
Oxervate (Pending Implementation) (Revised July 24, 2020)*
Oxycontin / Narcotic Analgesic (Revised March 29, 2019)*
Palforzia (Pending Implementation) (Revised October 8, 2021)*
PDE5-Inhibitors (Revised April 15, 2021)*
Phosphate Binders (Pending Implementation) (Revised August 31, 2021)*
Phosphate Binders (Revised January 30, 2020)*
Plavix (Pending Implementation) (Revised March 29, 2019)*
Promethazine Utilization (Revised March 29, 2019)*
Propylthiouracil (Revised March 29, 2019)*
Proton Pump Inhibitors (Pending Implementation) (Revised March 29, 2019)*
Pulmonary Hypertension Agents (Pending Implementation) (Revised February 13, 2020)*
Qelbree (Pending Implementation) (Revised July 28, 2021)*
Ranexa (Revised March 29, 2019)*
Retinoids (Pending Implementation) (Revised July 19, 2021)*
Savella (Pending Implementation) (Revised March 29, 2019)*
SGLT2 Agents (Pending Implementation) (Revised June 18, 2021)*
Sickle Cell Agents (Revised January 30, 2020)*
Symlin (Revised March 29, 2019)*
Synagis (Revised August 11, 2020)*
Thiazolidinediones (Revised November 11, 2020)*
Topical Acne Agents (Pending Implementation) (Revised July 19, 2021)*
Topical Immunomodulators (Revised June 24, 2020)*
Transthyretin Agents (Pending Implementation) (Revised October 8, 2021)*
Urea Cycle Disorder Agents (Pending Implementation) (Revised April 26, 2019)
Valturna (Retired) (Revised August 23, 2017)*
VMAT2 Inhibitors (Pending Implementation) (Revised October 15, 2021)*
VMAT2 Inhibitors (Revised June 24, 2020)*
Wakix (Pending Implementation) (Revised October 8, 2021)*
Xifaxan (Revised March 29, 2019)*
Xyrem (Pending Implementation) (Revised October 8, 2021)*
Xyrem (Revised March 29, 2019)*
Xyrem/Xywav (Pending Implementation) (Revised October 8, 2021)*
Zelboraf (Pending Implementation) (Revised October 8, 2021)*
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Updates to Medicaid Preferred Drug List Scheduled for Nov. 15
by CHRISTINA.FAULKNER on 10/19/2021
HHSC will publish an update to the Texas Medicaid Preferred Drug List (PDL) on Monday, Nov. 15. The update includes a change approved at the July 23, 2021 Drug Utilization Review (DUR) Board meeting. To learn more, refer to the Vendor Drug Program website at
Agenda for October Drug Utilization Review Board Meeting Now Available
by CHRISTINA.FAULKNER on 10/11/2021
The agenda for the Drug Utilization Review Board on Friday, October 22, 2021, is now available. Also available are instructions for submitting written materials to the board prior to the meeting and testifying on the day of the meeting. To learn more, refer to the Vendor Drug Program website at
Alinia Clinical Prior Authorization Criteria Revision Effective Nov. 23
by CHRISTINA.FAULKNER on 09/20/2021
HHSC will revise the Alinia (nitazoxanide) clinical prior authorization criteria effective Nov. 23, 2021. These changes reflect the generic tablets on the Medicaid formulary and remove the generic code numbers for the brand name. Additionally, HHSC will remove the criteria for the Alinia suspension and rename the document. The prior authorization is optional for managed care. To learn more, visit
Respiratory Syncytial Virus and Synagis Authorization During Summer and Winter 2021-22
by TALESHIA.CORE on 08/26/2021
As a result of the recent summertime resurgence in Respiratory Syncytial Virus (RSV) activity, HHSC began opening state regions gradually from June 21 through July 23, 2021. With the traditional 2021-22 RSV season approaching, all Texas DSHS regions will remain open. HHSC will consider the traditional 2021-22 RSV season a new season beginning October 1, 2021, separate from the unusual summer season. To learn more, visit
Duplicate Therapy Clinical Prior Authorization Criteria Revision Begins Oct. 19
by TALESHIA.CORE on 08/24/2021
Beginning Oct. 19, 2021, HHSC will remove the oral corticosteroids from the Duplicate Therapy clinical prior authorization criteria. This will allow for the approval of combination therapy with both oral and inhaled corticosteroids to treat asthma. The Duplicate Therapy clinical prior authorization is optional for MCOs. To learn more, visit
Changes to Hepatitis C Prior Authorization Criteria
by CHRISTINA.FAULKNER on 06/29/2021
Beginning September 1, 2021, Medicaid will expand coverage of the Hepatitis C virus clinical prior authorization criteria to include all metavir fibrosis scores. To learn more, visit
July 2021 Drug Utilization Review Board Meeting Summary
by CHRISTINA.FAULKNER on 08/06/2021
The Texas Drug Utilization Review Board met on Friday, July 23, to recommend Medicaid clinical prior authorizations and drugs for the preferred drug list. A summary of this meeting is now available from the Texas Vendor Drug Program website. The next meeting is scheduled for Friday, October 22, 2021. To learn more, visit
Nucala Clinical Prior Authorization Update Begins July 12
by CHRISTINA.FAULKNER on 06/18/2021
HHSC will revise the Nucala clinical prior authorization criteria section in the Monoclonal Antibody Agents for Asthma clinical prior authorization following the US Food and Drug Administration approved indications. Nucala is a monoclonal antibody prescribed as maintenance therapy for patients 6 years and older with severe eosinophilic asthma. However, the autoinjector and prefilled syringe products are only FDA-approved for at-home use for adults and adolescents age 12 and older. This clinical prior authorization is optional for MCOs. To learn more, visit
Enzymes Clinical Prior Authorization Criteria Revisions Effective June 30
by TANNER.BAIN on 04/21/2021
HHSC will revise the clinical prior authorization criteria guides for enzymes on June 30, 2021, per the recent US Food and Drug Administration changes. References to Adagen, Ceprotin, Fabrazyme, and Revcovi will change. To learn more, visit
Revisions to Cytokine and CAM Antagonists Prior Authorization Criteria Set for May 4
by TANNER.BAIN on 03/05/2021
HHSC will revise Cytokine and Cell-Adhesion Molecule (CAM) Antagonists clinical prior authorizations criteria on May 4, 2021, in accordance with the recent US Food and Drug Administration changes. This clinical prior authorization is optional for MCOs. To learn more, visit
Monoclonal Antibody for Asthma Prior Authorization Updates Set for April 6, 2021
by TANNER.BAIN on 02/11/2021
Fasenra (benralizumab) and Nucals (mepolizumab) are monoclonal antibody drugs approved for severe asthma treatment. On April 6, 2021, HHSC will make the following changes to the prior authorization criteria for Monoclonal Antibody Agents to enhance appropriate utilization per the US Food and Drug Administration’s approved indications and dosing. To learn more, visit
Clinical Prior Authorization Updates for Cystic Fibrosis Agents
by TANNER.BAIN on 01/29/2021
HHSC currently requires all MCOs to implement the Orkambi criteria of the current cystic fibrosis agents clinical prior authorization. On March 1, 2021, HHSC will update the clinical prior authorization, and all agents will be optional, with Orkambi no longer required. Also, the Food and Drug Administration recently expanded the indications for Kalydeco, Orkambi, Symdeko, and Trikafta. On April 6, 2021, HHSC will update the cystic fibrosis agents prior authorization criteria to reflect recent FDA-approved indication expansions. To learn more, visit